Protect from what? Need to be more specific. I use pyrethrin and consider it safe. I only use when needed. There are specific sprays for specific pests that are safe, like BT for cabbage loopers or corn worms. For non toxic general protection learn to use floating row covers to protect greens from flea beetles for instance. Around here that is the only way to go for that.

I am stealing these suggestions from the many organic gardening resources that I have: These are some ideas to get started with:

For Mildew & Black spot prevention: 1/2 skim milk to 1/2 water solution
For slugs: 1/2 ammonia to 1/2 water - spray directly on the slug is immediate, leave it there because this will fertilize the soil!
Chili powder keeps varmints and cats away from plants--
For worms on cabbage: spring the plant lightly with flour
For subterranean grub worms and pill bugs, bury thick slices of potatoes (stuck with skewers which appear as markers above the soil so you can find them), which will attract the worms, and then remove the potatoes a couple of weeks later.
For bacterial infections, you must remove and destroy the plant, and then wash your shoes and tools with 1 part bleach with 9 parts water (you should spray this on your shoes each day in the garden anyway). Use antibacterial solution on hands to prevent further infection of plants.
For uncontrollable weeds, use a propane flamer (like a torch) to burn the weeds, which does not contaminate the soil for other plants.
To get rid of beauty berry! Plant aromatic plants like zinnias, mint, basil, and scented geranniums, dill, parsley, chives, and radish to confuse insects away from more tender vegetables like tomatoes, squash, cucumbers.
Plant okra (stronger stalks) and carrot seeds around bell pepper and banana pepper (more tender stalks) to protect from wind and heavy rain damage.